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Abstract BACKGROUND: Fermentation of dietary fiber by the gut microbiota leads to the production of metabolites called short-chain fatty acids, which lower blood pressure and exert …
The lack of GPR41/43 expression in the immune compartment was sufficient to lead to a worsened hypertensive phenotype. We also demonstrate that GPR41/43 is, at least partially, …
School of Biological Sciences, Monash University - Cited by 592 - hypertension - immunology - genetics - microbiome - short-chain fatty acids
31 thg 1, 2025 · While in the absence of adequate dietary fibre, gut cells can become leaky and lead to generalised inflammation. Lead author Dr Rikeish Muralitharan said the findings …
The lack of GPR41/43 expression in the immune compartment was suficient to lead to a worsened hypertensive phenotype. We also demonstrate that GPR41/43 is, at least partially, responsible …
Recent evidence supports a role for the gut microbiota in hypertension, but whether ambulatory blood pressure is associated with gut microbiota and their metabolites remains unclear.
The lack of GPR41/43 expression in the immune compartment was sufficient to lead to a worsened hypertensive phenotype. We also demonstrate that GPR41/43 is, at least partially, …
In one of my recent publications in January 2025 published in Circulation Research, I demonstrate that host receptors to short-chain fatty acids (microbiome by-products) are protective in …
Professor Marques's Lab is now running a human clinical trial to better understand gut permeability in hypertension, and is starting in vitro tests of potential new drugs to bind to the...
20 thg 3, 2023 · R. Muralitharan, Rikeish. / GPR41/43 regulates blood pressure by improving gut epithelial barrier integrity to prevent TLR4 activation and renal inflammation. 2023. bioRxiv.
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